The contemporary mass post-truth information landscape involves substitution of facts and values with falsehoods, and more subtly, near-truths, which are covertly closer to truth than to frank lie, and for this reason more unrecognizable. Net identities, artificial intelligence, and machine learning contribute also to distortion of the capacity to discriminate between news and facts, and thence, to cognitive blurring, and even to failure of the reality testing. The cognitive confusion and the virtual reality communications reflect both on psychopathology and diagnostics. Rapid culture and identity transitions cause pathomorphosis of clinical pictures and illness behavior styles. The impact on the current trend for overdiagnosis of psychopathology and pathologization of existential human problems, as well as on stigma and mental health care, are presented and discussed. In the digital age, people frequently seek advice and help, and even online treatment, through the internet. Care however is needed because there are data that digital treatments which fail can interfere with patients seeking higher intensity and better evidenced treatments. Safeguards and solutions to this problem will be considered.